Investment adviser · CRD 118608

ORBIMED ADVISORS LLC

Investment adviser filing (IA)

NEW YORK, NY, United States · Form ADV filed Aug 18, 2026

Regulatory AUM: $20.6B
Client accounts: 32
Employees: 118
Advisory professionals: 86

Who they report serving

Form ADV · Item 5.D

Client types and their share of reported regulatory assets.

Client type	Clients	Regulatory assets	Share of AUM
Pooled investment vehicles	32	$20,607,970,000	100.0%

Filing source

Form ADV 2126532 · Aug 18, 2026 · Item 5.D

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

Private funds & service providers

33 Private funds

The count excludes feeder funds. Funds in the latest filing appear first, ordered by reported gross assets. Earlier funds retain their last reported values.

ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV OFFSHORE, LPPrivate Equity Fund · Last reported Aug 18, 2026$568MGross asset value

Feeder funds

ORBIMED RCO IV OFFSHORE FEEDER, LP

Fund administrator HEDGESERV (CAYMAN ) LTD. GEORGE TOWN, Cayman Islands Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian SILICON VALLEY BANK NEWTON, Massachusetts, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

Fund details & source

Fund ID: 805-4968769906
Reported beneficial owners: 154
Minimum commitment: $500K
Form D file number: 021-452404

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED PARTNERS MASTER FUND LIMITEDHedge Fund · Last reported Aug 18, 2026$535MGross asset value

Feeder funds

Fund administrator HEDGESERV (CAYMAN ) LTD. GEORGE TOWN, Cayman Islands Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian ABSA BANK (MAURITIUS) LIMITED EBENE, Mauritius Related to adviser: No

Custodian CITIBANK (CHINA) CO., LTD. SHANGHAI, China Related to adviser: No

Custodian CITIBANK (INDIA) N.A. MUMBAI, India Related to adviser: No

Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No

Custodian J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States Related to adviser: No

Custodian THE NORTHERN TRUST INTERNATIONAL BANKING CORPORATION JERSEY CITY, New Jersey, United States Related to adviser: No

Custodian U.S. BANK NEW YORK, New York, United States Related to adviser: No

Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States

Prime broker J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States

Provider details

Annual audit: Yes
Prime brokers: Yes
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

GOLDMAN SACHS & CO. LLC
SEC 8-129

J.P. MORGAN SECURITIES LLC
SEC 8-35008

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

J.P. MORGAN SECURITIES LLC
CRD 79 · SEC 8-35008

Fund details & source

Fund ID: 805-6802622809
Reported beneficial owners: 126
Minimum commitment: $1M
Form D file number: 021-129096
Form D file number: 021-91544

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED ROYALTY & CREDIT OPPORTUNITIES III, LPPrivate Equity Fund · Last reported Aug 18, 2026$359MGross asset value

Form D fundraising filings

OrbiMed Royalty & Credit Opportunities III, LP

Fund administrator SS&C TECHNOLOGIES, INC. NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian SILICON VALLEY BANK NEWTON, Massachusetts, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

Fund details & source

Fund ID: 805-7281770620
Reported beneficial owners: 113
Minimum commitment: $450K
Form D file number: 021-331673

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED PRIVATE INVESTMENTS V, LPOther Private Fund · Last reported Aug 18, 2026$328MGross asset value

Form D fundraising filings

OrbiMed Private Investments V, LP

Fund administrator SS&C TECHNOLOGIES, INC. NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian SILICON VALLEY BANK NEWTON, Massachusetts, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

Fund details & source

Fund ID: 805-7934003414
Reported beneficial owners: 462
Minimum commitment: $10M
Form D file number: 021-205773

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED ISRAEL PARTNERS II, L.P.Other Private Fund · Last reported Aug 18, 2026$298MGross asset value

Form D fundraising filings

OrbiMed Israel Partners II, L.P.

Fund administrator SS&C TECHNOLOGIES, INC. NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor BRIGHTMAN ALMAGOR ZOHAR & CO. TEL AVIV, Israel

Custodian BANK OF LEUMI LE-ISRAEL B.M. HAIFA, Israel Related to adviser: No

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian SILICON VALLEY BANK NEWTON, Massachusetts, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

BRIGHTMAN ALMAGOR ZOHAR & CO.
PCAOB 1197

JPMORGAN CHASE BANK, N.A.
LEI 7H6GLXDRUGQFU57RNE9

Fund details & source

Fund ID: 805-5094083814
Reported beneficial owners: 116
Minimum commitment: $5M
Form D file number: 021-253036

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED ASIA PARTNERS II, L.P.Other Private Fund · Last reported Aug 18, 2026$108MGross asset value

Form D fundraising filings

OrbiMed Asia Partners II, LP

Fund administrator SS&C TECHNOLOGIES, INC. NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian AFRASIA BANK LIMITED PORT LOUIS, Mauritius Related to adviser: No

Custodian CHINA INTERNATIONAL CAPITAL CORPORATION BEIJING, China Related to adviser: No

Custodian CITIBANK (INDIA), N.A. MUMBAI, India Related to adviser: No

Custodian CITIGROUP GLOBAL MARKETS INC. NEW YORK, New York, United States Related to adviser: No

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian SHANGHAI PUDONG DEVELOPMENT BANK SHANGHAI, China Related to adviser: No

Custodian SILICON VALLEY BANK NEWTON, Massachusetts, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

CITIGROUP GLOBAL MARKETS INC.
SEC 8-8177

JPMORGAN CHASE BANK, N.A.
LEI 7H6GLXDRUGQFU57RNE9

Fund details & source

Fund ID: 805-4969310917
Reported beneficial owners: 415
Minimum commitment: $10M
Form D file number: 021-201444

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

ORBIMED PARTNERS SPV, LTD.Hedge Fund · Last reported Aug 18, 2026$103MGross asset value

Fund administrator HEDGESERV (CAYMAN ) LTD. GEORGE TOWN, Cayman Islands Investor statements: Yes (provided to all investors) Related to adviser: No

Auditor KPMG LLP NEW YORK, New York, United States

Custodian JPMORGAN CHASE BANK, N.A. NEW YORK, New York, United States Related to adviser: No

Custodian THE NORTHERN TRUST INTERNATIONAL BANKING CORPORATION JERSEY CITY, New Jersey, United States Related to adviser: No

Provider details

Annual audit: Yes
Prime brokers: No
Custodians: Yes
Administrator other than the adviser: Yes
External marketing: No

KPMG LLP
PCAOB 185

Fund details & source

Fund ID: 805-3533159706
Reported beneficial owners: 130
Minimum commitment: $100K

Form ADV 2126532 · Aug 18, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

Services & filing details

Most recent filing: Aug 18, 2026. View historical filings

Reported services

Pooled investment vehicle management

Compensation

Percentage of assets · Performance-based

Principal office

601 LEXINGTON AVENUE, 54TH FLOOR
NEW YORK, NY, 10022, United States

CRD 118608

Filing source

Form ADV 2126532 · Aug 18, 2026 · Items 1 & 5

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.