Form D · Hedge Fund

Palo Alto Advanced Life Sciences Offshore Fund, Ltd.

George Town, Grand Cayman, E9 · CIK 0001636553

Offering snapshot reported Feb 25, 2026 · SEC filing

Reported sold
$74.7M
Indefinite offering
Investors reported
16
Form D · investor count
Minimum accepted
$5M
Reported outside-investor minimum
First sale
Mar 1, 2015
As reported in this filing

Fundraising history

Reported sold
Reported amount sold by Form D filing date$0$37.3M$74.7MMar 13, 2015: $4,750,000.00Mar 13, 2015Mar 9, 2016: $11,250,000.00Jun 6, 2016: $11,250,000.00Jun 6, 2017: $13,250,000.00Apr 2, 2018: $15,250,000.00Apr 2, 2019: $23,950,000.00Mar 31, 2020: $64,325,000.00Mar 29, 2021: $74,325,000.00Mar 16, 2022: $74,655,000.00Mar 3, 2023: $74,655,000.00Mar 1, 2024: $74,655,000.00Feb 26, 2025: $74,655,000.00Feb 25, 2026: $74,655,000.00Feb 25, 2026

Dates are filing dates, not cash receipt dates. Decreases are reported revisions, not evidence of withdrawals. Separate offering histories are not added together.

What changed?

Latest filing versus its linked predecessor, where available.

No comparable changes in the displayed metrics.

Filing history

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FiledFiling typeReported soldChange vs linked filingInvestorsSource
Feb 25, 2026Amendment$74,655,000$0vs Feb 26, 202516SEC filing
Feb 26, 2025Amendment$74,655,000$0vs Mar 1, 202416SEC filing
Mar 1, 2024Amendment$74,655,000$0vs Mar 3, 202316SEC filing
Mar 3, 2023Amendment$74,655,000$0vs Mar 16, 202216SEC filing
Mar 16, 2022Amendment$74,655,000$330,000vs Mar 29, 202116SEC filing
Mar 29, 2021Amendment$74,325,000$10,000,000vs Mar 31, 202016SEC filing
Mar 31, 2020Amendment$64,325,000$40,375,000vs Apr 2, 201914SEC filing
Apr 2, 2019Amendment$23,950,000$8,700,000vs Apr 2, 201813SEC filing
Apr 2, 2018Amendment$15,250,000$2,000,000vs Jun 6, 201711SEC filing
Jun 6, 2017Amendment$13,250,000$2,000,000vs Jun 6, 20167SEC filing
Jun 6, 2016Amendment$11,250,000$0vs Mar 9, 20165SEC filing
Mar 9, 2016Amendment$11,250,000$6,500,000vs Mar 13, 20155SEC filing
Mar 13, 2015Initial$4,750,000No comparison3SEC filing

Offering details

Securities
Equity, Pooled investment fund
Exemptions
06b, 3C, 3C.7
Duration over one year
Yes
Business combination
No
Sales commissions
$0 (estimated)
Finders' fees
$0 (estimated)
Form D file number
021-235882
The issuer does not pay sales commissions or finders' fees expenses. The investment adviser of the issuer pays a portion of the management fees it receives to the entities listed in Item 12.

Sales compensation recipients

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RecipientCRDAssociated broker-dealer
MMX Global Partners, LLC000286531
Morgan Stanley Smith Barney LLC000149777
Crewe Capital000152527
Capital Connect, LLC000329399

Source: Form D, filed Feb 25, 2026. Minimum accepted may differ from a standard advertised minimum.

Fund connections

No confirmed ADV fund connection is available for this issuer.

People & organizations

Current and past Form D appearances. These existing records do not establish a person's current role or uniquely identify them across issuers.

People and organizations reported in Form D filings
NameReported role
Roger H. Hanson Director
Patrick Y. Lee Director
Cary Marr Director
N/A Palo Alto Investors, Llc Executive
N/A Palo Alto Investors, Lp Executive
Jonathan Roney Director
Anthony Joon Yun Executive

Issuer details

Industry: Pooled Investment Fund (See others in industry)

Address:
C/O Walkers Corporate Limited 190 Elgin Avenue
George Town, Grand Cayman, E9, KY1 - 9008