Investment adviser · CRD 158149

BAKER BROTHERS INVESTMENTS

Investment adviser filing (IA)

BAKER BROS. ADVISORS LP

NEW YORK, NY, United States · Form ADV filed Mar 27, 2026

Regulatory AUM
$28.1B
Form ADV · Item 5.F
Client accounts
2
Accounts, not individual clients
Employees
60
Reported in this filing
Advisory professionals
17
Investment advisory functions

Who they report serving

Form ADV · Item 5.D

Client types and their share of reported regulatory assets.

Client typeClientsRegulatory assetsShare of AUM
Pooled investment vehicles2$28,147,892,952100.0%
Filing source

Form ADV 2060926 · Mar 27, 2026 · Item 5.D

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

Private funds & service providers

7 Private funds

The count excludes feeder funds. Funds in the latest filing appear first, ordered by reported gross assets. Earlier funds retain their last reported values.

BAKER BROTHERS LIFE SCIENCES, L.P.Hedge Fund · Last reported Mar 27, 2026$25.8BGross asset value

Form D fundraising filings

Baker Brothers Life Sciences LP

Feeder funds

Fund administrator SS&C FINANCIAL SERVICES LLC NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No
Fund administrator SS&C FUND SERVICES (CAYMAN) LTD GRAND CAYMAN, Cayman Islands Investor statements: Yes (provided to all investors) Related to adviser: No
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Auditor ERNST & YOUNG LTD GRAND CAYMAN, Cayman Islands
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian JPMORGAN CHASE BANK N.A. COLUMBUS, Ohio, United States Related to adviser: No
Custodian J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States Related to adviser: No
Custodian THE BANK OF NEW YORK MELLON NEW YORK, New York, United States Related to adviser: No
Custodian THE NORTHERN TRUST COMPANY CHICAGO, Illinois, United States Related to adviser: No
Marketer IBK SECURITIES CO., LTD SEOUL, Korea, South Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Prime broker J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
Yes
External marketing
Yes

ERNST & YOUNG LLP
PCAOB 42

ERNST & YOUNG LTD
PCAOB 1655

GOLDMAN SACHS & CO. LLC
SEC 8-129

JPMORGAN CHASE BANK N.A.
LEI 7H6GLXDRUGQFU57RNE97

J.P. MORGAN SECURITIES LLC
SEC 8-35008

THE BANK OF NEW YORK MELLON
LEI HPFHU0OQ28E4NONFVK49

THE NORTHERN TRUST COMPANY
LEI 6PTKHDJ8HDUF78PFWH30

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

J.P. MORGAN SECURITIES LLC
CRD 79 · SEC 8-35008

Fund details & source
Fund ID
805-9378432489
Reported beneficial owners
392
Minimum commitment
$20M
Form D file number
021-560745
Form D file number
021-560749

Form ADV 2060926 · Mar 27, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

667, L.P.Hedge Fund · Last reported Mar 27, 2026$2.34BGross asset value
Fund administrator SS&C FINANCIAL SERVICES LLC NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian JPMORGAN CHASE BANK N.A. COLUMBUS, Ohio, United States Related to adviser: No
Custodian J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States Related to adviser: No
Custodian THE BANK OF NEW YORK MELLON NEW YORK, New York, United States Related to adviser: No
Custodian THE NORTHERN TRUST COMPANY CHICAGO, Illinois, United States Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Prime broker J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
Yes
External marketing
No

ERNST & YOUNG LLP
PCAOB 42

GOLDMAN SACHS & CO. LLC
SEC 8-129

JPMORGAN CHASE BANK N.A.
LEI 7H6GLXDRUGQFU57RNE97

J.P. MORGAN SECURITIES LLC
SEC 8-35008

THE BANK OF NEW YORK MELLON
LEI HPFHU0OQ28E4NONFVK49

THE NORTHERN TRUST COMPANY
LEI 6PTKHDJ8HDUF78PFWH30

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

J.P. MORGAN SECURITIES LLC
CRD 79 · SEC 8-35008

Fund details & source
Fund ID
805-7902319250
Reported beneficial owners
13
Minimum commitment
$40M

Form ADV 2060926 · Mar 27, 2026 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

14159, L.P.Hedge Fund · Last reported Mar 25, 2020$17MGross asset value
Fund administrator SS&C FINANCIAL SERVICES LLC NEW YORK, New York, United States Investor statements: Yes (provided to all investors) Related to adviser: No
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian JPMORGAN CHASE BANK N.A. COLUMBUS, Ohio, United States Related to adviser: No
Custodian J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States Related to adviser: No
Custodian THE NORTHERN TRUST COMPANY CHICAGO, Illinois, United States Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Prime broker J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
Yes
External marketing
No

ERNST & YOUNG LLP
PCAOB 42

GOLDMAN SACHS & CO. LLC
SEC 8-129

JPMORGAN CHASE BANK N.A.
LEI 7H6GLXDRUGQFU57RNE97

J.P. MORGAN SECURITIES LLC
SEC 8-35008

THE NORTHERN TRUST COMPANY
LEI 6PTKHDJ8HDUF78PFWH30

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

J.P. MORGAN SECURITIES LLC
CRD 79 · SEC 8-35008

Fund details & source
Fund ID
805-9816274483
Reported beneficial owners
9
Minimum commitment
$40M

Form ADV 1385208 · Mar 25, 2020 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

BAKER/TISCH INVESTMENTS L.P.Hedge Fund · Last reported Mar 18, 2019$11MGross asset value
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Prime broker J.P. MORGAN SECURITIES LLC NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
No
External marketing
No

ERNST & YOUNG LLP
PCAOB 42

GOLDMAN SACHS & CO. LLC
SEC 8-129

J.P. MORGAN SECURITIES LLC
SEC 8-35008

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

J.P. MORGAN SECURITIES LLC
CRD 79 · SEC 8-35008

Fund details & source
Fund ID
805-3184499373
Reported beneficial owners
6
Minimum commitment
$40M

Form ADV 1279622 · Mar 18, 2019 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

BAKER BROS. INVESTMENTS, L.P.Hedge Fund · Last reported Mar 18, 2019$9.82MGross asset value
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian THE BANK OF NEW YORK MELLON NEW YORK, New York, United States Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
No
External marketing
No

ERNST & YOUNG LLP
PCAOB 42

GOLDMAN SACHS & CO. LLC
SEC 8-129

THE BANK OF NEW YORK MELLON
LEI HPFHU0OQ28E4NONFVK49

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

Fund details & source
Fund ID
805-6854596471
Reported beneficial owners
3
Minimum commitment
$40M

Form ADV 1279622 · Mar 18, 2019 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

BAKER BIOTECH FUND II(A), L.P.Hedge Fund · Last reported Mar 19, 2015$9.39MGross asset value
Auditor ERNST & YOUNG LLP NEW YORK, New York, United States
Custodian GOLDMAN, SACHS & CO. NEW YORK, New York, United States Related to adviser: No
Prime broker GOLDMAN, SACHS & CO. NEW YORK, New York, United States
Provider details
Annual audit
Yes
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
No
External marketing
No

GOLDMAN, SACHS & CO.
SEC 8-129

GOLDMAN, SACHS & CO.
CRD 361 · SEC 8-129

Fund details & source
Fund ID
805-5375553944
Reported beneficial owners
4
Minimum commitment
$40M

Form ADV 893905 · Mar 19, 2015 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

BAKER BROS. INVESTMENTS II, L.P.Hedge Fund · Last reported Mar 18, 2019$1.22MGross asset value
Custodian GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States Related to adviser: No
Custodian THE BANK OF NEW YORK MELLON NEW YORK, New York, United States Related to adviser: No
Prime broker GOLDMAN SACHS & CO. LLC NEW YORK, New York, United States
Provider details
Annual audit
No
Prime brokers
Yes
Custodians
Yes
Administrator other than the adviser
No
External marketing
No

GOLDMAN SACHS & CO. LLC
SEC 8-129

THE BANK OF NEW YORK MELLON
LEI HPFHU0OQ28E4NONFVK49

GOLDMAN SACHS & CO. LLC
CRD 361 · SEC 8-129

Fund details & source
Fund ID
805-8976652096
Reported beneficial owners
2
Minimum commitment
$40M

Form ADV 1279622 · Mar 18, 2019 · Schedule D 7.B.(1)

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.

Services & filing details

Most recent filing: Mar 27, 2026. View historical filings

Reported services

Pooled investment vehicle management

Compensation

Percentage of assets · Performance-based

Principal office

860 WASHINGTON STREET, 3RD FLOOR
NEW YORK, NY, 10014, United States

CRD 158149

Filing source

Form ADV 2060926 · Mar 27, 2026 · Items 1 & 5

Official IAPD profile (latest public filing). Values are the most recently reported in our imported data; the public profile may show a newer filing.